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Daicel chiral columns offer excellent resolution of racemates, rapid and easy method development, plus durability and long service life. Daicel chiral columns are essential tools in the pharmaceutical industry. CHIRALPAK® and CHIRALCEL®, well known as chiral chromatography columns, are trademarks of Daicel. Inside the chiral columns are chiral resolving agents Chiral Stationary Phases (CSPs). Developed in the 1980s using Daicel expertise in cellulose chemistry is available as analytical columns and/or small-scale separation as well as for commercial separations. Featuring Simulated moving bed (SMB) as a continuous column separation which allows MT scale production and currently having the largest SMB chiral production in the world of >100MT.

Recent product developments consist of immobilized CSP, CHIRALPAK® IA, IB, IC, ID, IE and IF. These allow use of a wider range of chromatographic solvents. 

Daicel Chiral Columns Chemistries

  • Immobilized type
    These immobilized CSPs allow the use of a highly extended range of solvents.
  • Normal Phase
    CSPs are most widely used for chiral separation in the world.
  • Reversed-Phase
    For reverse phase use.
    AGP/CBH/HSA
    Protein-based chiral HPLC columns.
  • CROWNPAK
    These columns contain a chiral crown ether as a chiral selector which is a coated onto a 5µm silica support.
  • Qseries
    These columns are enatioselective weak anion-exchange (AX) HPLC columns.

  • Others
    HPLC columns other than the above
  • Accessories
    The analytical columns should be used in series with an appropriate guard cartridge or columns.
  • SFC
    Super critical fluid is a special phase which has either gas and liquid character but different from these.